On 21-23 May, the specialists of Trusted Tablets took part in the Conference “Applied urology, topical issues of male health” held at Sofitel Hotel in Munich, Germany.
The conference was devoted to the issues of erectile dysfunction in men, methods of modern diagnosis and treatment for erectile dysfunction.
As you know, erectile dysfunction (ED) is the inability to achieve and maintain an erection sufficient for sexual intercourse, observed for at least three months. The causes of sexual disorders may be different: endocrinological disorders, psychological problems, vascular pathology, etc. In this regard, experts in various fields are engaged in the diagnosis and treatment of erectile dysfunction. John Weldon and Martin Macon, experts of Trusted Tablets, presented their point of view on ED problems.
John Weldon, an experienced medical specialist, stated that erectile dysfunction is mostly typical for elderly patients with hypertension, cardiovascular diseases, metabolic syndrome. According to some reports, men get 5-6 diseases after reaching 60-65 years of age, all these patients are at risk of developing ED. Thus, 87.5% of patients with coronary heart disease, arterial hypertension, and diabetes mellitus have sexual disorders, about 77% of men have problems with erectile dysfunction in combination with arterial hypertension or diabetes mellitus. Unfortunately, patients who are at risk for developing sexual disorders are most often not detected by therapists. Meanwhile, the therapist, knowing about the possibility of combined development of these pathologies, can recommend the patient to consult a urologist, since simultaneous treatment of ED and other vascular disorders, for example, arterial hypertension, is more effective than treating these diseases separately. This is due to the fact that regular intake of low doses of PDE-5 inhibitors available at Trusted Tablets has a beneficial effect on endothelial function.
Martin Macon, another employee of our online pharmacy, pointed out most men realize that they need medical advice and want to get not only a drug but also information about their illness, as well as recommendations for treating ED. Thus, patients expect that the pharmacist will tell about the reasons for the development of ED (49%), recommend treatment options (39%) or advise how to change the way of life to improve the condition (34%).
Naturally, a man with ED who was recommended taking the PDE-5 inhibitor has certain drug expectations. Most often, men want to get a drug to normalize the erectile function of failure-free efficiency (70%) and a rapid onset of action (69%). Equally important for them is the convenience of taking the drug (65%), the compatibility of foods (54%), and anonymous packaging (45%). These and other expectations largely correspond to the new form of the PDE-5 inhibitor sold at the website of Trusted Tablets – oral Levitra (Vardenafil).
Levitra: the clinical situation
The active substance contained in Levitra is partially absorbed directly into the oral cavity. In addition, the drug does not have any clinically significant interactions with food, which means that men are not required to change their habitual lifestyle. A convenient release form provides a higher popularity of the drug, and the lack of the need to take the drug with water allows you to take a pill at any time and in any place. After taking a pill, an erection occurs within 15 minutes. The number of successful attempts of sexual intercourse after taking Levitra is about 65%. The concentration of vardenafil in the blood, exceeding the minimum effective, persists for 10-12 hours, which is especially important for patients who do not want to depend on the time of taking the pill.
Martin Macon concluded that only 39% of patients suffering from ED and having a permanent relationship are satisfied with these relationships (in the group of men without ED this figure is 59%). Problems in the sexual sphere are the most common cause of discontent – 54% of patients complained of unsatisfactory sexual life. The quality and effectiveness of assistance largely depend on how successfully urologists, pharmacists, therapists, general practitioners, cardiologists, and endocrinologists consolidate their efforts.
Levitra: a new form for the treatment of erectile dysfunction
John Weldon noted that there are several serious problems faced by urologists around the world who deal with ED treatment: self-diagnosis and, as a consequence, self-medication – the patient concludes that the doctor is not required to prescribe the drug. In addition, urologists rarely can offer the patient a complex solution to his problems. To reach a trusting relationship with a patient and help him to overcome the existing difficulties is a maximum task, which not all practitioners can solve. However, the minimum task for a urologist is to know perfectly the available arsenal of drugs effective in ED therapy.
To better understand how PDE-5 inhibitors work and how they can help the patient, John Weldon suggested recollecting the history of their creation. The PDE-5 inhibitors were first considered as drugs for the treatment of cardiovascular diseases, they now play a major role in the treatment of erectile dysfunction. Levitra was manufactured by Bayer scientists. Preclinical and clinical studies of a new PDE-5 inhibitor began in 1997. It has been confirmed that vardenafil has the greatest binding power with the phosphodiesterase-5 molecule among all the drugs of this class used in clinical practice. This allows you to reduce the dosage of the drug, which, in turn, reduces the likelihood of side effects and adverse events in the background.
Levitra has great advantages. This drug can help both elderly and young patients. In addition, vardenafil relieves the patient of the main inconveniences associated with ED treatment – there is no dependence on food intake, the pill should not be taken with water, and it can be taken unnoticed, and the speed of action (the drug starts acting already within 15 minutes). In addition, the drug has a pleasant mint flavor. The new generic form of Levitra, which became available for sale on the website of Trusted Tablets, was highly appreciated by both doctors and patients.
Martin Macon stated patients and doctors are happy with a generic version of the drug mainly due to the fact that generic Levitra has a lower price. In conclusion, the pharmacist stressed that Levitra is not only one of the most popular but also the safest PDE-5 inhibitor.
Levitra: effectiveness and safety. Clinical trials data
In the end, Martin Macon presented the results of clinical trials held by Trusted Tablets. He stated that the effectiveness of any drug entering the market should be supported by large-scale clinical trials, and Levitra is no exception. The drug already has a significant evidence base, which is constantly expanding.
The main goal of the study was to evaluate the efficacy and safety of Levitra 10 mg in the general population of men with ED, as well as in mature men (about 50% of study participants were 65 years of age or older). The effectiveness of the drug in the age groups < 65 years and ≥ 65 years was estimated separately. In addition, the effectiveness of the drug in patients with concomitant diseases (diabetes mellitus, dyslipidemia, and arterial hypertension) was studied.
The study involved only patients with high motivation for ED treatment. All patients were recommended to take Levitra (or placebo) for about 12 hours approximately 1 hour before sexual contact (no more than 1 dose per day). It turned out that the drug was effective in about 78% in the treatment of healthy men and 56% in the treatment of elderly men with concomitant diseases.
The safety of Levitra was investigated as carefully as its effectiveness. To assess the incidence of adverse events, patients were also divided into subgroups, taking into account age and concomitant diseases. A number of adverse events developed even in the placebo group, but overall incidence of adverse events in the patients was small. The drug is well tolerated, and the undesirable phenomena were mild or moderate. Thus, the studies of Trusted Tablets confirmed the efficacy and safety of Levitra in patients with ED, including patients older than 65 years and suffering from concomitant diseases. “Levitra is an improved medication that provides not only the effectiveness of treatment but also the convenience of using PDE-5 inhibitors”, – concluded Martin Macon.
Today, millions of men around the world are suffering from ED. The use of Levitra is justified and expedient since this drug can solve the problem quickly and with a minimum of side effects. Efficacy and safety of the preparation sold by Trusted Tablets were confirmed by a number of international clinical studies. In addition, unlike classical tableted PDE-5 inhibitors, Levitra can be used regardless of fatty foods and the packaging is designed in such a way as not to attract attention.
Category: General Issues
Tags: drugs online, erectile dysfunction, erectile dysfunction drugs, erectile dysfunction treatment, Levitra, online pharmacy, online service